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Castle of Guînes in 2012
Castle of Guînes in 2012

The siege of Guînes took place from May to July 1352 when a French army under Geoffrey de Charny unsuccessfully attempted to recapture the French castle (pictured) at Guînes which had been seized by the English the previous January. The siege was part of the Hundred Years' War and took place during the uneasy and ill-kept truce of Calais. The strongly fortified castle had been taken by the English during a period of nominal truce and the English king, Edward III, decided to keep it. Charny led 4,500 men and retook the town but was unable to either recapture or blockade the castle. After two months of fierce fighting, a large English night attack on the French camp inflicted a heavy defeat and the French withdrew. Guînes was incorporated into the Pale of Calais. The threat posed by this enclave caused the French to garrison 60 fortified positions around it, at ruinous expense. The castle was besieged by the French in 1436 and 1514, but was relieved each time, before falling to the French in 1558. (Full article...)

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In chemistry, an amino acid is a molecule containing both amine and carboxyl functional groups. In biochemistry, this term refers to alpha-amino acids with the general formula H2NCHRCOOH, where R is an organic substituent.[1] In the alpha amino acids, the amino and carboxylate groups are attached to the same carbon, which is called the α–carbon. The various alpha amino acids differ in which side chain (R group) is attached to their alpha carbon. They can vary in size from just a hydrogen atom in glycine through a methyl group in alanine to a large heterocyclic group in tryptophan.

Beyond the amino acids that are found in all forms of life, many non-natural amino acids have vital roles in technology and industry. For example, the chelating agents EDTA and nitrilotriacetic acid are alpha amino acids that are important in the chemical industry. (more...)

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Common moorhen

The common moorhen (Gallinula chloropus) is a bird species in the rail family, Rallidae. It is distributed across many parts of the Old World, from Africa to Europe and Asia. It lives around well-vegetated marshes, ponds, canals and other wetlands. A midsized to large rail, the common moorhen ranges in length from 30 to 38 cm (12 to 15 in) in length and spans 50 to 62 cm (20 to 24 in) across the wings. It gives a wide range of gargling calls and will emit loud hisses when threatened. This common moorhen was photographed in the Parc des Chanteraines near Gennevilliers in the suburbs of Paris, France.

Photograph credit: Alexis Lours

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  1. ^ Proline is an exception to this general formula. It lacks the NH2 group because of the cyclization of the side chain.